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Preclinical research suggests that restoring lymphatic flow in the brain has the potential to address a range of neurodegenerative diseases, such as Alzheimer s and Parkinson s diseases, and associated neuroinflammation Additionally, research found that improving lymphatic flow could enhance the efficacy of antibody therapies against aberrant proteins, potentially opening a new avenue for disease management
PureTech Health plc (Nasdaq: PRTC, LSE: PRTC) ( PureTech or the Company ), a clinical-stage biotherapeutics company dedicated to discovering, developing and commercializing highly differentiated medicines for devastating diseases, today announced the publication of preclinical research in Nature which suggests that enhancing meningeal lymphatic drainage could improve clinical outcomes for Alzheimer s disease, either alone or in combination with passive immunotherapies such as antibodies directed at amyloid b
PureTech Announces Annual Results for Year Ended December 31, 2020
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Strong capital base and cash runway extended into the first quarter of 2025, with PureTech level cash and cash equivalents of $443.4 million as of March 31, 2021
1 ($349.4 million as of December 31, 2020
2) and consolidated cash and cash equivalents of $486.5 million as of March 31, 2021
3 ($403.9 million as of December 31, 2020
4)
Advancement of Wholly Owned Pipeline with four clinical trial initiations and one successful readout, with three clinical trials ongoing
Significant milestones across PureTech’s Founded Entities including one FDA Clearance for Marketing, two European Marketing Authorizations, initiation of a Phase 3 program, $247.8 million raised in 2020
5 and $473.2 million raised in the 2021 post-period