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Beam makes $120M bet that GuideTx s tech brings gene editing beyond the liver

MedCity News Beam makes $120M bet that GuideTx’s tech brings gene editing beyond the liver Base-editing biotech Beam Therapeutics engineered an all-stock buyout of Guide Therapeutics, a startup that finds, in vivo, the lipid nanoparticles that can deliver genetic medicines. Beam said GuideTx’s tech helps it address tissue types throughout the body, not just the liver. Shares0   The next hurdles for gene-editing medicines are therapies that do their work inside the patient. But so far, biotechs have had a hard time developing such in vivo therapies that target anything other than the liver. Beam Therapeutics has acquired a startup whose technology could deliver the biotech’s genetic medicines to more tissues in the body, broadening the potential to address more diseases.

The week ahead: UK unemployment rate; HSBC, Lloyds results

The week ahead: UK unemployment rate; HSBC, Lloyds results
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Bluebird scrambles to find out if its gene therapy caused cancer in clinical trial

Cancer is a known risk of lentiviral-based gene therapies. Though bluebird says its gene therapy is engineered to avoid that risk, the company is suspending two clinical trials pending the outcome of its inquiry.

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