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Listen • 4:42 Melissa Cruz elevated her arm after donating COVID-19 convalescent plasma in April 2020, as phlebotomist Jenee Wilson shut down the collection equipment at Bloodworks Northwest in Seattle. More than half a million Americans have received an experimental treatment for COVID-19 called convalescent plasma. But a year into the pandemic, it s not clear who, if anyone, benefits from it. That uncertainty highlights the challenges scientists have faced in their attempts to evaluate COVID-19 drugs. On paper, treatment with convalescent plasma makes good sense. The idea is to take blood plasma from people who have recovered from COVID-19 and infuse it into patients with active infections. The antibodies in the donated plasma, in theory, would help fight the virus.

New yorkUnited statesUnited kingdomNicole bouvierDerek angusMichael bloombergArturo casadevallKevin schulman at stanford universityUniversity of pittsburghDrug administrationJohns hopkins bloomberg school of public healthIcahn schoolMount sinai hospitalWest africaNew york cityJohns hopkins bloomberg school