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Freeze-Drying Diagnostics for COVID-19: Formulation Development and Selecting a Lyophilizer
Although it is considered a relatively gentle drying process, there are still risks and pitfalls when applying lyophilization to biomolecular reagents in diagnostic tests, which are different from the freeze-drying of generic pharmaceuticals.
The reagents generally utilized in PCR and ELISA based diagnostic kits for diseases like COVID-19 usually to contain labile components, like antibodies that are used to test for a patient s response to the virus, which can be difficult to stabilize for commercial use, or enzymes that must be preserved for longevity in the supply chain.
Dr. Kevin Ward, Director of Research and Development at Biopharma Group, UK, recently gave a webinar looking at numerous aspects of formulation and cycle development in the lyophilization of diagnostic reagents. These aspects included those needed for COVID-19 testing, which may be different to regular diagnostics; this
Coastal destruction is no laughing matter
Coastal destruction is no laughing matter
December 15, 2020 10.00pm
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The Age, email letters@theage.com.au. Please include your home address and telephone number.
ENVIRONMENT
Coastal destruction is no laughing matter
The storm surges and inundation being experienced in southern Queensland are a result of more intense storms arising from climate change coinciding with a king tide. Scientists have been warning of this for decades, a consequence of global warming driven by too much carbon dioxide in the atmosphere. Not only have these warnings been ignored, but Peter Dutton famously joked about the inundation concerns from our Pacific island neighbours. Are they daring to laugh now?
Strikers Fox Valley start One Community, One Club campaign Since 2004, Strikers Fox Valley has occupied a 50,000-square-foot indoor training facility on Kirk Road in Geneva. Courtesy of Wellspring Creative Communications, iWellspring.com.
Updated 12/12/2020 12:32 AM
Strikers Fox Valley is announcing its One Community, One Club campaign to enhance its image as the one of the top sports training organization in the western suburbs of Chicago.
The campaign, which kicks off the nonprofit s 32nd year of club soccer for youth, is designed to bring Strikers message of better players make better people to a broader audience throughout the suburbs.
Long recognized as a leader in youth training and especially soccer for the Fox Valley region, Strikers Fox Valley was established in the 1980s out of a need to bring high-level training and the experience of traveling soccer to suburban communities that did not have that opportunity.