Hallan las células cerebrales más vulnerables al Alzheimer notimerica.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from notimerica.com Daily Mail and Mail on Sunday newspapers.
Scientists have identified the brain cells that are most vulnerable to Alzheimer s disease for the first time, in what s being referred to as the holy grail of dementia studies.
The brain cells lie in a region known as the entorhinal cortex, which controls memory, navigation and time perception, and are the first to be killed off by the disease.
The researchers hope the findings could be used to develop a new and much more targeted approach to developing therapies to slow or prevent the spread of Alzheimer s disease.
The brain cells lie in a region known as the entorhinal cortex, which controls memory, navigation and time perception, and are the first to be killed off by the disease
A major mystery in Alzheimerâs disease research is why some brain cells succumb to the creeping pathology of the disease years before symptoms first appear, while others seem impervious to the degeneration surrounding them until the diseaseâs final stages. Â
An image of human brain samples used to study why some brain cells are more vulnerable to Alzheimerâs disease than others.
Image by Rana Eser, UCSF Grinberg lab
Now, in a study published Jan. 10, 2021, in
Nature Neuroscience, a team of molecular biologists and neuropathologists from the UCSF Weill Institute for Neurosciences have joined forces to identify for the first time the neurons that are among the first victims of the disease ââ¯accumulating toxic âtanglesâ and dying off earlier than neighboring cells. Â