Thirteen new Alzheimer s genes identified in first-of-its-kind human genome study eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease In animal models, the new compound modulated a key enzyme, reducing or eliminating production of problematic protein fragments; human clinical trials needed March 02, 2021 | Scott LaFee
News release
Amyloid plaques are pathological hallmarks of Alzheimer’s disease (AD) clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.
In a new study, published March 2, 2021 in the
Journal of Experimental Medicine (JEM), researchers at University of California San Diego School of Medicine, Massachusetts General Hospital and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.
Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer s Disease scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.
Grandmother inspires Easton student’s Alzheimer’s project
Wicked Local
EASTON – When she was young, Ana Dias said, she loved to visit her grandparents, who lived in a large Portuguese community in Ludlow.
“My grandmother was an amazing cook and she would always make traditional Portuguese dishes,” Dias said. “I thought it was so cool that my grandparents lived in a community so rich with culture. Both of my grandparents and all of my other relatives in Ludlow spoke Portuguese, and there were Portuguese butcher shops, bakeries, and restaurants all through the town. My grandparents helped connect me to my Portuguese heritage and I wish that I had more of a connection to it today.”
Study finds site of immune surveillance of the brain, points to new ways to target brain inflammation
January 27, 2021 SHARE Immune cells (yellow and purple) fill a sinus (teal) in the outer layer of the meninges, the tissue that surrounds the brain and spinal cord. Researchers at Washington University School of Medicine in St. Louis have found that immune cells stationed in such sinuses monitor the brain and initiate an immune response if they detect a problem. (Image: Justin Rustenhoven)
Alzheimer’s disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There’s growing evidence that immune cells and molecules play a key role in normal brain development and function as well. But at the core of the burgeoning field of neuroimmunology lies a mystery: How does the immune system even know what’s happening in the brain? Generations of students have been taught that the brai