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How an Aggressive Form of Prostate Cancer Flips the Switch on Therapy
Source: Steve Gschmeissner/Science Photo Library/Getty Images
January 6, 2021
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Neuroendocrine prostate cancer (NEPC) is a high-risk, lethal subset of disease, that may arise de novo or in patients previously treated with hormonal therapies for prostate adenocarcinoma as a mechanism of resistance. However, the clinical features of NEPC are poorly defined. Now, researchers from the Flinders Health and Medical Research Institute in South Australia report they have identified a new mechanism in which prostate cancer cells can “switch” character and become resistant to therapy.
Their findings are published in