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Twist Bioscience Launches Industry-Leading NGS Methylation Detection System for Liquid Biopsy Cancer Analysis and Epigenetic Studies

Posted on 323 Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced the launch of the Twist NGS Methylation Detection System, a robust, end-to-end sample preparation and target enrichment solution for identifying methylated regions in the human genome. DNA methylation plays a key role in many biological processes including cancer. When present on a single nucleotide, a methyl group can alter genetic behavior without changing the DNA sequence. Analyzing these methylation patterns provides unique understanding of disease pathology, including the ability to screen for cancer earlier using blood samples known as “liquid biopsies.”

(TWST) - Twist Bioscience Launches Methylation Detection Systems

Early Release - Mycobacterium bovis Infection in Free-Ranging African Elephants - Volume 27, Number 3—March 2021 - Emerging Infectious Diseases journal

Mycobacterium bovis infection in wildlife species occurs worldwide. However, few cases of M. bovis infection in captive elephants have been reported. We describe 2 incidental cases of bovine tuberculosis in free-ranging African elephants ( Loxodonta africana) from a tuberculosis-endemic national park in South Africa and the epidemiologic implications of these infections. Tuberculosis (TB), caused by the human pathogen Mycobacterium tuberculosis, is a recognized disease in human-managed and wild Asian elephants ( Elephas maximus) and African elephants ( Loxodonta africana) ( 3). Previous findings demonstrate the importance of human-elephant interfaces for transmission. However, range countries for African and Asian elephants also have high burdens of bovine TB, caused by

Low Cost Universal Optical DNA Rapid Detection System for Pathogens Including COVID-19

Low Cost Universal Optical DNA Rapid Detection System for Pathogens Including COVID-19 11 Feb 2021 OZ Optics offers an exceptionally affordable yet reliable optical DNA/detection system based on Loop-mediated isothermal amplification (LAMP). Much like polymerase chain reaction (PCR) amplification, LAMP is a highly sensitive method of DNA detection that creates millions to billions of copies of a target DNA from a minute amount of sample RNA or DNA. However unlike PCR, LAMP applies an isothermal process that does not require expensive and complex equipment, as well as time consuming thermal cycling. It is a more cost-effective and rapid system. LAMP is especially ideal for rapid diagnosis of pathogens or infectious diseases, with results usually within 30 minutes and for high viral loads less than 20 minutes. 

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