New proton therapy targets treatment-resistant cancer cells
Mayo Clinic researchers have developed a novel proton therapy technique to more specifically target cancer cells that resist other forms of treatment. The technique is called LEAP, an acronym for biologically enhanced particle therapy. The findings are published today in
Cancer Research, the journal of the American Association for Cancer Research.
The human body receives tens of thousands of DNA lesions per day from a variety of internal and external sources. Therefore, cells have evolved complex repair pathways to efficiently repair damaged DNA. Defects in these repair pathways can lead to the development of diseases, including cancer, says Dr. Mutter.
Novel hydrogel slowly releases RNA nanovaccines to shrink tumors
Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer. Now, researchers reporting in ACS
Nano Letters have developed a hydrogel that, when injected into mice with melanoma, slowly released RNA nanovaccines that shrank tumors and kept them from metastasizing.
Cancer immunotherapy vaccines work similarly to mRNA vaccines for COVID-19, except they activate the immune system to attack tumors instead of a virus. These vaccines contain mRNA that encodes proteins made specifically by tumor cells. When the mRNA enters antigen-presenting cells, they begin making the tumor protein and displaying it on their surfaces, triggering other immune cells to seek and destroy tumors that also make this protein. However, mRNA is an unstable molecule that is quickly degraded
New 3D imaging technique helps detect breast cancer, COVID-19, other diseases
A research team led by UMass Lowell is pioneering a new 3D imaging technique to better detect breast cancer and other diseases, including COVID-19.
The noninvasive medical technology uses specialized contrasting dye that recognizes breast cancer cells, allowing practitioners to better visualize human tissue inside the body. The dye amplifies the X-ray signal in tumors when used together with a state-of-the-art computed tomography (CT) scanner, called a photon-counting spectral CT, which produces multi-colored, 3D images. The contrast agents, combined with spectral CT and machine learning, could lead to a more precise diagnosis of the disease and assist significantly in early intervention, said UMass Lowell Chemistry Assistant Prof. Manos Gkikas, who is leading the project, which is funded by a three-year, $750,000 grant from the Massachusetts Life Sciences Center.
Winter storm also wreaking havoc on fuel supply
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KATY, Texas – The Buc-ee’s in Katy was a popular site Wednesday night with people from across southeast Texas looking for gas. Jose Ortiz drove all the way from Eagle Lake just to fill two one-gallon cans.
“I had to drive about 50 miles to get here,” Ortiz said. “50 miles I had to drive to get these two gallons so I can run a generator overnight.”
For Briana Jones, who drove from Memorial, the quest was for gas and food.
“It’s bad,” she said. “We can’t live like this. We’re trying to go to Buc-ee’s to get some food. We’re just trying to scavenge around to see who has food.”
Retail wrap: Grand at Aliana inks new stores
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The Grand at Aliana, a development of NewQuest Properties at West Grand Parkway South and West Airport Boulevard in Richmond, will welcome anchor tenants Michaels, Ross Dress for Less and Ulta in March 2021.NewQuest Properties
Bath & Body Works leased 4,000 square feet in the Grand at Aliana, a development of NewQuest Properties at West Grand Parkway South and West Airport Boulevard in Richmond. Josh Friedlander and David Meyers of NewQuest Properties represented the landlord. Mike Wheeler of Streetwise Retail Advisors represented the Bath & Body Works, which is targeting an April opening. Additionally,