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Mouse study: gabapentin prevents harmful structural changes in spinal cord

 E-Mail IMAGE: Phillip Popovich is a professor and chair of Ohio State s Department of Neuroscience and Executive Director of the Belford Center for Spinal Cord Injury at The Ohio State University College. view more  Credit: The Ohio State University Wexner Medical Center COLUMBUS, Ohio - Research led by The Ohio State University Wexner Medical Center and College of Medicine found that the widely prescribed pain-relief drug gabapentin can prevent harmful structural changes in the injured spinal cords of mice, and also block cardiovascular changes and immune suppression caused by spinal cord injury. Gabapentin is often prescribed as a treatment for pain, but if it is given early after injury - before symptoms develop - it can also limit structural changes in nerve cells. We show that these benefits remain even one month after stopping gabapentin treatment in spinal injured mice. We believe that gabapentin could be repurposed as a prophylactic therapy that can prevent

Some young pot abusers up self-harm risk

VW independent/submitted information COLUMBUS Youths with mood disorders who use and abuse cannabis (marijuana) have a higher risk for self-harm, death by all causes and death by unintentional overdose and homicide, according to research led by The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine. Study findings are published in  JAMA Pediatrics. “Marijuana use and addiction is common among youth and young adults with mood disorders, but the association of this behavior with self-harm, suicide, and overall mortality risk is poorly understood in this already vulnerable population,” said lead author Cynthia Fontanella, an associate professor in the department of psychiatry and behavioral health at Ohio State. “These findings should be considered as states contemplate legalizing medical and recreational marijuana, both of which are associated with increased cannabis use disorder.” 

Youths with mood disorders who use marijuana at higher risk of death, self-harm

 E-Mail Youths with mood disorders who use and abuse cannabis (marijuana) have a higher risk for self-harm, death by all causes and death by unintentional overdose and homicide, according to research led by The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine. Study findings are published in the Marijuana use and addiction is common among youth and young adults with mood disorders, but the association of this behavior with self-harm, suicide and overall mortality risk is poorly understood in this already vulnerable population. These findings should be considered as states contemplate legalizing medical and recreational marijuana, both of which are associated with increased cannabis use disorder, said lead author Cynthia Fontanella, an associate professor in the department of psychiatry and behavioral health at Ohio State.

Village of West Alexandria cited by Ohio Auditor s office

Village of West Alexandria cited by Ohio Auditor’s office By Anthony Baker - abaker@aimmediamidwest.com An audit of the Village of West Alexandria alleges multiple anomalies, including a finding for recovery in the amount of $3,326. Anthony Baker | The Register-Herald WEST ALEXANDRIA Ohio Auditor of State Keith Faber issued a press release detailing the results of an audit of the Village of West Alexandria on Tuesday, Jan. 5. The audit, which covers the years 2017 and 2018, uncovered multiple anomalies, including a finding for recovery in the amount of $3,326. A finding for recovery is issued when public funds are determined to have been misspent or misappropriated, according to information on the Auditor of State’s website. Penalties, late fees, and interest charges levied by state agencies are an example of unnecessary expenditures which do not serve a proper public purpose, and may result in a finding for recovery.

No 18 Buckeyes Host Sun Devils in VCA

COLUMBUS, Ohio The No. 18 Ohio State men’s hockey team (3-5-0, 3-5-0-0-1-0 B1G) wraps up the first part of its season with a nonconference series against Arizona State (3-6-1) this week. The teams will meet at 5:30 p.m. Thursday and Friday in Value City Arena. Both games will be streamed through BTN Plus and aired on Ohio State Radio, with Herb Howenstine and John Mowat on the call. The Ohio State Department of Athletics has determined fans, including family members of the players and coaching staffs of teams competing on campus through the end of 2020, will not be permitted into any university sporting event. The decision aligns with the Columbus Department of Health’s stay at home advisory.

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