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Shionogi s Novel Antibiotic, Fetcroja (cefiderocol), Has Been Selected by UK s NICE / NHSE&I as Part of an Antimicrobial Subscription Style Reimbursement Model Enterobacterales and non-fermenting species such as P. aeruginosa, A. baumannii, and S. maltophilia, makes them difficult to treat and results in high mortality rates. 7,8 The World Health Organization have identified carbapenem-resistant strains of Enterobacterales, A. baumannii as the top priority in the research and development of new antibiotics. 9 Cefiderocol is the first antibiotic to address all three major mechanisms of carbapenem-resistance and is an important new treatment option to address this urgent unmet need. 10 Cefiderocol Cefiderocol is the world s first siderophore cephalosporin antibiotic with a novel mechanism of entry through the outer membrane of Gram-negative pathogens by using the bacteria s own iron uptake system to gain cell entry, acting like a Trojan horse.

United kingdomCity ofMatt hancockTakuko sawadaShionogi europeNicola lilleyCleve clinMark hillNational institute for healthClinical development to address unmet medicalShionogi co ltdWorld health organizationEuropean centre for disease preventionNational health service englandFor united kingdom medicalPharma trade media