Researchers Identify PH Probe for Dynamics Inside the Brain by Angela Mohan on December 28, 2020 at 12:00 PM
Miniature pH probe helps in real-time investigations of extracellular dynamics in the deep brain structures.
In our healthy brains, abnormalities in chemistry can lead to chronic brain disorders like mental illness, glioma, and seizures. Associating brain pH fluctuations with signaling and functions provides knowledge of the effect of pH on brain operations.
In spite of technical progression in electrical recordings of the brain and chemical monitoring technologies, limitations remain in measuring the chemical signaling, especially the pH of living organisms, i.e. in vivo.
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.
Miniature pH probe allows real-time analysis of pH dynamics in deep brain structures
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.
In our brain, over billions of dedicated workers neurons and glial cells form complex and efficient networks that constantly communicate with each other via subtle chemical signals to govern our behavioral output.
Brain chemistry is the fundamental language among brain cells. In our healthy brains, the chemistry stays relatively neutral and must constantly regulate the acid-alkaline fluctuations; otherwise, it can lead to chronic brain disorders such as mental illness, glioma, and seizures.
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Eavesdropping on pH Levels Inside Brain
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.
In our brain, over billions of dedicated workers – neurons and glial cells – form complex and efficient networks that constantly communicate with each other via subtle chemical signals to govern our behavioral output.
The brain chemistry is the fundamental language among brain cells. In our healthy brains, the chemistry stays relatively neutral and must constantly regulate the acid-alkaline fluctuations; otherwise it can lead to chronic brain disorders such as mental illness, glioma and seizures. Correlating in brain pH fluctuations with brain signaling and functions, therefore, provides a clearer understanding of the influence of pH on how our brain operates and how it malfunctions in a diseased state.