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Affinia Therapeutics Presents New Data and Updates on AAV Platform at American Society of Gene and Cell Therapy Annual Meeting

Share: WALTHAM, Mass., May 13, 2021 (GLOBE NEWSWIRE) Affinia Therapeutics, an innovative gene therapy company with a proprietary platform for rationally designed adeno-associated virus (AAV) vectors and gene therapies for rare and non-rare diseases, today announced results from preclinical studies presented in poster and oral sessions at the American Society of Gene and Cell Therapy (ASGCT) 24 Challenges in achieving adequate expression in the central nervous system (CNS) with conventional AAV vectors have limited the use of gene therapy to address many devastating rare and non-rare CNS diseases. Affinia Therapeutics presented data in a poster session on its proprietary AAV vector Anc80L65 showing superiority to AAV9 in various non-human primate (NHP) CNS regions after a single intrathecal injection. When delivered via lumbar puncture, Anc80L65 demonstrated up to 32-fold higher RNA expression versus AAV9 delivered via the more invasive intracisternal route of administration. An

United statesCharlie albrightDeepak groverKevin olivieriLisa stanekAmerican society of geneNetwork analysis of complex novelVector library datasetsAmerican societyCell therapyAffinia therapeuticsNonhuman primates resultsMore widespread gene transfer throughoutCentral nervous system comparedNetwork analysisComplex novel

Low glucose levels might assist muscle repair, finds study

Tokyo [Japan], April 4 (ANI): A new study has revealed a new benefit of keeping sugar at bay. Researchers from Tokyo Metropolitan University have shown that skeletal muscle satellite cells, key players in muscle repair, proliferate better in low glucose environments.

Yasuko manabeNobuharul fujiiYasuro furuichiTokyo metropolitan universityAssistant professor yasuro furuichiAssociate professor yasuko manabeProfessor nobuharul fujiiLow glucoseBone healthProfessor yasuro furuichiSkeletal muscleLatest science related studyடோக்கியோ பெருநகர பல்கலைக்கழகம்எலும்பு ஆரோக்கியம்எலும்பு தசைசமீபத்தியது அறிவியல் தொடர்புடையது படிப்பு

Avidity Biosciences Reports Fourth Quarter and Year-End 2020 Financial Results and Recent Highlights

Share this article Share this article LA JOLLA, Calif., March 15, 2021 /PRNewswire/ Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company pioneering a new class of oligonucleotide-based therapies called Antibody Oligonucleotide Conjugates (AOCs™), today reported financial results for the fourth quarter and year ended December 31, 2020 and highlighted recent corporate progress. In 2020, we made significant advances across our AOC pipeline and platform. Our work supports Avidity s evolution to a clinical-stage company as we plan to advance AOC 1001 into the clinic in the second half of this year and progress our FSHD and DMD programs, said Sarah Boyce, President and Chief Executive Officer. Our discovery efforts continue to focus on expanding our AOC platform into additional muscle diseases and other tissues as we begin to realize our vision of profoundly improving people s lives by revolutionizing the delivery of RNA treatments.

United statesTamar thompsonJean kimAmy conradMike macleanEli lillyBristol meyers squibbSarah boyceMyotonic dystrophy clinical research networkPrnewswire avidity biosciences incExchange commissionDevelopment rd expensesAvidity biosciences incDiverse team members to managementAntibody oligonucleotide conjugatesChief executive

Canarias24Horas com - El Hospital Dr Negrín, galardonado en los premios nacionales TOP 20 en el área Músculo Esquelético

Canarias24Horas com - El Hospital Dr Negrín, galardonado en los premios nacionales TOP 20 en el área Músculo Esquelético
canarias24horas.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from canarias24horas.com Daily Mail and Mail on Sunday newspapers.

Skeletal muscleSurgery orthopedicPlastic surgeryAnatomy pathologicalOncology medicalBefore body partsSurgery complex muscleBefore body parts professionalNew editionNervous systemTracks urinaryஎலும்பு தசைநெகிழி அறுவை சிகிச்சைபுற்றுநோயியல் மருத்துவபுதியது பதிப்புபதட்டமாக அமைப்பு

Dos áreas del Negrín y Materno, galardonados como los mejores de España

Dos áreas del Negrín y Materno, galardonados como los mejores de España
canarias7.es - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from canarias7.es Daily Mail and Mail on Sunday newspapers.

Spain generalUniversity to large canary islands insularSkeletal muscleAwards hospitals topIslands canaryIslands balearicSurgery orthopedicPlastic surgeryAnatomy pathologicalOncology medicalMarie towersஸ்பெயின் ஜநரல்எலும்பு தசைநெகிழி அறுவை சிகிச்சைபுற்றுநோயியல் மருத்துவ