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Researchers identify anti-inflammatory prodrug Minnelide with potential against SARS-CoV-2 A team of scientists from the United States has recently investigated the efficacy of an anti-inflammatory prodrug Minnelide in treating coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Using a transgenic mouse model of COVID-19, they have observed that treatment with Minnelide reduces viral load and inflammation in the lungs and improves survival. The study is currently available on the Background As of May 10, 2021, globally, there have been over 157 million confirmed infections of SARS-CoV-2, causing over 3.28 million deaths. The clinical characteristics of SARS-CoV-2 infection range from asymptomatic or mildly symptomatic to severe, lethal illness. In severe cases, mortality mainly occurs due to pneumonia-induced acute respiratory distress syndrome (ARDS) or vascular thrombotic events.

United statesSanchari sinha duttaExperimental schematicCytokine milieuMice treatedPulmonary cytokine milieuஒன்றுபட்டது மாநிலங்களில்சஞ்சரி சீன்ஹா தத்தாஎலிகள் சிகிச்சை