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Researchers use silkworm silk for 3D muscle modeling
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Researchers Use Silkworm Silk to Model Muscle Tissue
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Scientists use silk from transgenic silkworm to grow skeletal muscle cells
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IMAGE: Silk fibers are wound around an acrylic chassis to produce a three-dimensional cell culture device. Skeletal muscle cells grown on silkworm silk proved to more closely mimic human skeletal muscle. view more
Credit: Matt Jensen
News Release LOGAN, UT Mar. 9, 2021 Researchers at Utah State University are using silkworm silk to grow skeletal muscle cells, improving on traditional methods of cell culture and hopefully leading to better treatments for muscle atrophy.
When scientists are trying to understand disease and test treatments, they generally grow model cells on a flat plastic surface (think petri dish). But growing cells on a two-dimensional surface has its limitations, primarily because muscle tissue is three-dimensional. Thus, USU researchers developed a three-dimensional cell culture surface by growing cells on silk fibers that are wrapped around an acrylic chassis. The team used both native and transgenic silkworm silk, the latter produ