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FDA Passes on Inclisiran; COVID Myocarditis in Athletes; Cath Lab Distress

email article In a surprise move, FDA declined to approve lipid lowering drug inclisiran over inability to inspect the manufacturing facility. ( Endpoints News) Life expectancy rose slightly in 2019, with heart disease still the top cause of mortality, but COVID-19 is likely to change all of that for 2020. ( AP, CDC) A cardiac MRI study of 59 athletes with mild or asymptomatic COVID-19 turned up myocarditis in two (3%), one of whom subsequently developed symptomatic low ejection fraction. Focal late gadolinium enhancement was equally common in them as in control athletes (22% vs 24%). ( Circulation) Fully 95% of cardiac cath lab nurses and technologists reported poorer morale and increased mental distress, including depression in 36%, due to the pandemic, according to a national survey. (

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