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Dana-Farber researchers present key studies at ASCO annual meeting 20 May

Dana-Farber researchers present key studies at ASCO annual meeting 20 May
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GRA unveils initiative to fight sickle cell disease

GRA unveils initiative to fight sickle cell disease Gov. Brian Kemp makes announcement; Eminent Scholar chair named for Rep. Calvin Smyre May 13, 2021 11:00 ET | Source: Georgia Research Alliance Georgia Research Alliance Atlanta UNITED STATES Atlanta, GA, May 13, 2021 (GLOBE NEWSWIRE) Seeking to capitalize on Georgia’s strengths in university research and healthcare, the Georgia Research Alliance today introduced a five-year initiative to advance exploration into sickle cell disease (SCD), including new treatments and therapies. The announcement, made by Gov. Brian Kemp at a gathering in Columbus, Ga., included news that a GRA Eminent Scholar chair would be created at Morehouse School of Medicine (MSM), Emory University and Children’s Healthcare of Atlanta (CHOA) – and named for state Rep. Calvin Smyre of Columbus, currently the longest-serving member of the Georgia General Assembly. 

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways. Mostly. So far, these promising drugs haven t been very useful in getting through to the well-protected brain to treat tumors or other maladies. Now a multi-institutional team of researchers, led by Costas Arvanitis at the Georgia Institute of Technology and Emory University, has figured out a way: using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors.

Breaching blood-brain barrier to deliver precious payloads

Georgia Institute of Technology RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways. Mostly. So far, these promising drugs haven’t been very useful in getting through to the well-protected brain to treat tumors or other maladies. Now a multi-institutional team of researchers, led by Costas Arvanitis at the Georgia Institute of Technology and Emory University, has figured out a way: using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors.

Breaching the blood-brain barrier to deliver precious payloads

 E-Mail IMAGE: Georgia Tech Mechanical Engineering Ph.D. student Yutong Guo (left) and her mentor, assistant professor Costas Arvanitis, have developed a way to use ultrasonics to treat brain disease. view more  Credit: Ashley Ritchey, Georgia Tech RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways. Mostly. So far, these promising drugs haven t been very useful in getting through to the well-protected brain to treat tumors or other maladies.

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