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Ultra-high Field MRI Detects Subtle Differences of Brain s Hippocampus in People with Down Syndrome

Ultra-high Field MRI Detects Subtle Differences of Brain’s ‘Hippocampus’ in People with Down Syndrome Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus a region of the brain tied to memory and learning. April 29, 2021   Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus a region of the brain tied to memory and learning.

Ultra-High Field MRI Provides a Closer Look of the Hippocampus in Down Syndrome

Ultra-High Field MRI Provides a Closer Look of the Hippocampus in Down Syndrome April 30, 2021 Brain MRI images. [Getty Images] Has a certain smell ever triggered a memory from your childhood? The hippocampus plays a part in that connection as it plays a critical role in the formation, organization, and storage of new memories as well as connecting certain sensations and emotions to these memories. Previous studies have found that memory impairment in Down syndrome (DS) is linked to inhibition in the hippocampus. Now a new study by researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals, and collaborators detected subtle differences in the structure and function of the hippocampus.

Ultra-high field MRI detects differences in brain s hippocampus

Case Western Reserve University CLEVELAND–Using ultra-high field magnetic resonance imaging (MRI) to map the brains of people with Down syndrome (DS), researchers from Case Western Reserve University, Cleveland Clinic, University Hospitals and other institutions detected subtle differences in the structure and function of the hippocampus–a region of the brain tied to memory and learning. Such detailed mapping, made possible by the high-powered MRI, is significant because it allowed the research team to better understand how each subregion of the hippocampus in people with DS is functionally connected to other parts of the brain. “The ultimate goal of this approach is to have an objective technique to complement neuropsychological assessments to measure the functional skills of those with DS,” said Alberto Costa, professor of pediatrics and psychiatry at the Case Western Reserve University School of Medicine and the study’s senior author.

Ultra-high field MRI detects differences in brain s hippocampus

Ultra-high field MRI detects differences in brain s hippocampus
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