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Anticancer drug may improve outcome for severe COVID-19 patients
Treating severe COVID-19 patients with the anticancer drug bevacizumab may reduce mortality and speed up recovery, according to a small clinical study in Italy and China that was led by researchers at Karolinska Institutet in Sweden between February and April 2020. On average, blood oxygen levels, body temperature and inflammatory markers significantly improved in patients treated with a single dose of bevacizumab in addition to standard care. The research is published in Nature Communications.
Yihai Cao, photo: Ulf Sirborn
“To reduce COVID-19 mortality, we aim to develop an effective therapeutic paradigm for treating patients with severe COVID-19,” says corresponding author Yihai Cao, professor of vascular biology at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet. “Our findings suggest that bevacizumab plus standard care is highly beneficial for patients with severe
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IMAGE: Daniel Simon, associate professor in the Laboratory of Organic Electronics, Department of Science and Technology at Linköping University. view more
Credit: Thor Balkhed
Researchers at Linköping University, Sweden, have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. The new technique may reduce drug side effects, and in the long term, ion pumps may help patients with symptoms of neurological diseases for which effective treatments are not available. The results have been published in
Science Advances.
Approximately 6% of the world s population suffer from neurological diseases such as epilepsy, Parkinson s disease, and chronic pain. However, currently available drug delivery methods - mainly tablets and injections - place the drug in locations where it is not required. This can lead to side effects that harm the patient.
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