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Messenger RNA role in cancer gene therapy

Messenger RNA role in cancer gene therapy
dovepress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from dovepress.com Daily Mail and Mail on Sunday newspapers.

Chengdu
Sichuan
China
Germany
New-york
United-states
Japan
Shanghai
Coomassie
Ashanti
Ghana
Beijing

Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration

Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration
sciencemag.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencemag.org Daily Mail and Mail on Sunday newspapers.

Bloomington
Kansas
United-states
Dsred-clontech
T-dawson-addgene
Kansas-state-university
Laboratory-animals
Michaelj-fox-foundation-addgene
Cell-signaling-technology
National-institutes-of-health
University-of-connecticut-school-medicine
Drosophila-genomics-resource-center

The Covered-Up Crimes of Vaccine-Maker Pfizer – Just Another "Too-Big-To-Fail" American Corporation

The Covered-Up Crimes of Vaccine-maker Pfizer – Just Another “Too-Big-to-Fail” American Corporation This column high-lights the unethical/criminal attempts (of both the Trump-orchestrated, Biden-endorsed and Big Pharma-implemented Operation Warp-Speed, the unethical plan to totally skip both short-and long-term animal safety and efficacy studies) in order to promote potentially dangerous Covid-19 vaccines for both human adults and children. Here is a very telling Announcement from the the American Academy of Pediatrics (AAP) website (May 4, 2021). Be aware that the AAP membership relies on routine vaccinations for a large portion of the annual revenues) “Children ages 2-11 could potentially be eligible for (the still-experimental) COVID-19 vaccine this fall. Pfizer Chairman and CEO Albert Bourla, DVM, PhD (Doctor of Veterinary Medicine!),

New-jersey
United-states
Alabama
Rhode-island
Pennsylvania
Parsippany
Michigan
Connecticut
American
Albert-bourla
Garyg-kohls
Ronald-reagan

Frontiers | Excitatory Repetitive Transcranial Magnetic Stimulation Over Prefrontal Cortex in a Guinea Pig Model Ameliorates Tinnitus

2School of Biological Sciences, University of Western Australia, Crawley, WA, Australia 3Perron Institute for Neurological and Translational Research, Crawley, WA, Australia Tinnitus, a phantom auditory perception that can seriously affect quality of life, is generally triggered by cochlear trauma and associated with aberrant activity throughout the auditory pathways, often referred to as hyperactivity. Studies suggest that non-auditory structures, such as prefrontal cortex (PFC), may be involved in tinnitus generation, by affecting sensory gating in auditory thalamus, allowing hyperactivity to reach the cortex and lead to perception. Indeed, human studies have shown that repetitive transcranial magnetic stimulation (rTMS) of PFC can alleviate tinnitus. The current study investigated whether this therapeutic effect is achieved through inhibition of thalamic hyperactivity, comparing effects of two common clinical rTMS protocols with sham treatment, in a guinea pig tinnitus model. An

Germany
Australia
Somersby
New-south-wales
Bruel
Mecklenburg-vorpommern
United-states
Glenorie
Denmark
United-kingdom
Missouri
Praha

Frontiers | A Smartphone App for Individual Xylazine/Ketamine Calculation Decreased Anesthesia-Related Mortality in Mice

2Laboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil 3Faculty of Medical Sciences, University of Campinas, Campinas, Brazil 4Laboratory of Digital Signal Processing in Real Time, School of Electrical and Computer Engineering, University of Campinas, Campinas, Brazil 5Department of Chemical and Biomolecular Engineering, University of Nebraska, Lincoln, NE, United States Currently, experimental animals are widely used in biological and medical research. However, the scientific community has raised several bioethical concerns, such as the number of animals required to achieve reproducible and statistically relevant results. These concerns involve aspects related to pain, discomfort, and unwanted animal loss. Retrospectively, we compare two different approaches for anesthesia dosage: a mobile app for dose calculation and a standard dose calculation. A total of 939 C57BL/6J and Swiss mice were analyzed. We collected data on

Switzerland
Amorari
Amazonas
Brazil
Washington
United-states
Denver
Colorado
Langley
Campinas
Sãpaulo
Swiss

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