Ethical arguments have been made for and against infecting individuals with a potentially deadly virus
This study, UK officials say, will streamline and improve vaccine testing and development
The UK is officially moving forward with the world’s first Covid-19 human challenge trial, in which healthy volunteers will deliberately be exposed to SARS-CoV-2, the virus that causes Covid disease, in a carefully controlled setting.
Kicking off in the next few weeks, the government announced on Wednesday that the study will include up to 90 healthy adult volunteers aged 18–30 years, who are at the lowest risk of harm from Covid-19.
The researchers aim to establish the smallest amount of virus it takes to sicken someone, and hope that their work will aid Covid vaccine and therapy research.
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Ninety British volunteers will be deliberately infected with Covid-19 after scientists were given the green light to run the world s first human coronavirus trial.
Trial volunteers will stay at London s Royal Free hospital for two and a half weeks.
The study aims to find the smallest dose needed to trigger a Covid-19 infection, the BBC reports.
Virologist Dr Andrew Catchpole says the risk in the trial is believed to be incredibly small due to the trial s participants being young and healthy adults.
One of the participants includes Alastair Fraser-Urquhart, who believes the trial will help shorten the pandemic.
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A group of daring volunteers will soon become infected with Covid-19 on purpose.
They’re young. They’re healthy. And they want scientists to give them a candidate vaccine and then deliberately expose them to the coronavirus, so we can all find out faster whether the vaccine is effective.
This is called a human challenge trial, and it’s set to kick off in the UK within a month, now that an ethics board has given it the necessary approval. Scientists have run such trials in the past for influenza, malaria, typhoid, dengue, and cholera, but this will be the world’s first for Covid-19.