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 E-Mail MRSA skin infections are often treated with intravenous injection of antibiotics, which can cause significant side effects and promote the development of resistant bacterial strains. To solve these problems, researchers at Karolinska Institutet in Sweden are developing a microneedle patch that delivers antibiotics directly into the affected skin area. New results published in Advanced Materials Technologies show that the microneedle patch effectively reduces MRSA bacteria in the skin. MRSA (methicillin resistant Staphylococcus aureus) skin infections are potentially lethal, especially in patients with compromised immune systems. Vancomycin is one of the main treatments and is given as an intravenous injection. The reason the antibiotic is not given locally is because of its low ability to penetrate the skin. It is not given orally either because of poor absorption through the gut. The problem with systemic administration is that it often results in significant side effec

Karolinska institutetLiv eidsmoKeira melicanJill ziesmerGeorgiosa sotiriouNele johanna hempelPoojabahen tajparaMarcus ehrstrGeorgios sotiriouSwedish research councilDepartment of microbiologyEuropean research councilWorld economic forumSwedish foundation for strategic researchAdvanced materials technologiesCell biology