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Some sperm use poison to outrace their competitors

Some sperm use poison to outrace their competitors By (0) Researchers say that the sperm wining the race to the egg often effectively poisons its competitors on the way. File Photo by Sebastian Kaulitzki/Shutterstock Feb. 4 (UPI) It turns out that the sperm that win the race to the egg use variants of genetic factors, called distorters, to poison their competitors, according to new research. Experiments with mouse models suggest a genetic factor called t-haplotype is essential to the production of progressive sperm the ones capable of winning the race Advertisement T-haplotype genes regulate the synthesis of a molecule called RAC1, and the experiments detailed Thursday in the journal PLOS Genetics showed progressive sperm motility requires just the right amount of RAC1.

Alexandra amaralBernhard herrmannInstitute of medical geneticsMax planck institute for molecular geneticsMax planck instituteMolecular geneticsMedical geneticsHuman geneticsஅலெக்சாண்ட்ரா அமரல்பெர்ன்ஹார்ட் ஹெர்மன்நிறுவனம் ஆஃப் மருத்துவ ஜெநெடிக்ஸ்மூலக்கூறு ஜெநெடிக்ஸ்மருத்துவ ஜெநெடிக்ஸ்மனிதன் ஜெநெடிக்ஸ்

Some sperms poison their competitors

A genetic factor helps sperm cells outcompete their peers Competition among sperm cells is fierce – they all want to reach the egg cell first to fertilize it. A research team from Berlin now shows in mice that the ability of sperm to move progressively depends on the protein RAC1. Optimal amounts of active protein improve the competitiveness of individual sperm, whereas aberrant activity can cause male infertility. In direct competition, t-sperm outcompete their normal peers (+) in the race for the egg cell with genetic tricks, letting them swim in circles. © MPI f. Molecular Genetics/ Alexandra Amaral It is literally a race for life when millions of sperm swim towards the egg cells to fertilize them. But does pure luck decide which sperm succeeds? As it turns out, there are differences in competitiveness between individual sperm. In mice, a “selfish” and naturally occurring DNA segment breaks the standard rules of genetic inheritance – and awards a s

Alexandra amaralBernhard herrmannInstitute of medical genetics at charitMax planck institute for molecular geneticsMax planck instituteMolecular geneticsMedical geneticsஅலெக்சாண்ட்ரா அமரல்பெர்ன்ஹார்ட் ஹெர்மன்நிறுவனம் ஆஃப் மருத்துவ ஜெநெடிக்ஸ் இல் அறம்மூலக்கூறு ஜெநெடிக்ஸ்மருத்துவ ஜெநெடிக்ஸ்

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