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New drug combination targets prostate cancer on two front, study finds

Don t show me this message again✕ The international phase three trial involved 200 sites in 26 countries (PA) Patients with particularly aggressive prostate cancers can be treated more effectively by a combination of existing targeted medicine and an experimental new drug, new research suggests. Researchers looked at the efficacy of the targeted hormone drug abiraterone together with a new drug called ipatasertib in patients with advanced prostate cancer who had received no prior treatment. Abiraterone is a standard medicine taken by many people with advanced prostate cancer. The study, published in The Lancet, found using both medications extended the time before the cancer progressed and spread further.

New drug combination attacks prostate cancer on two fronts – study

New drug combination attacks prostate cancer on two fronts – study (David Davies/PA) Men with particularly aggressive prostate cancers can be treated more effectively by combining an existing targeted medicine with an experimental drug, new research suggests. Using both medications extended the time before prostate cancers progressed and spread further in men whose tumours lacked a gene known as PTEN. This is one of the most commonly deleted tumour suppressor genes – which often function to restrain inappropriate cell growth and division – in cancer. Researchers assessed the efficacy of the targeted hormone drug abiraterone – standard medicine for many men with advanced prostate cancer – together with a new drug called ipatasertib in men with advanced prostate cancer who had received no prior treatment.

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