New drug combination attacks prostate cancer on two fronts – study (David Davies/PA)
Men with particularly aggressive prostate cancers can be treated more effectively by combining an existing targeted medicine with an experimental drug, new research suggests.
Using both medications extended the time before prostate cancers progressed and spread further in men whose tumours lacked a gene known as PTEN.
This is one of the most commonly deleted tumour suppressor genes – which often function to restrain inappropriate cell growth and division – in cancer.
Researchers assessed the efficacy of the targeted hormone drug abiraterone – standard medicine for many men with advanced prostate cancer – together with a new drug called ipatasertib in men with advanced prostate cancer who had received no prior treatment.
New drug cocktail gives hope to men with most aggressive prostate cancer
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Neglect in basic care contributed to death of woman in hospital – coroner
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Neglect in basic care contributed to death of woman in hospital – coroner
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