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Benarkah Daun Pepaya Bisa Obati Demam Berdarah?

Menpan RB usulkan ASN tersangkut jual beli vaksin COVID-19 dipecat

Menteri Pendayagunaan Aparatur Negara dan Reformasi Birokrasi (Menpan RB) Tjahjo Kumolo mengusulkan tiga orang oknum Aparatur Sipil Negara (ASN) yang terlibat jual beli vaksin COVID-19 secara ilegal di wilayah Sumatera Utara dipecat.

Merck Says Phase 3 KEYNOTE-522 Trial Met Dual Primary Endpoint In Patients With Breast Cancer

Merck Says Phase 3 KEYNOTE-522 Trial Met Dual Primary Endpoint In Patients With Breast Cancer KENILWORTH (NJ) (dpa-AFX) - Merck & Co., Inc. (MRK), known as MSD outside the U.S. and Canada, announced Thursday positive results from the pivotal neoadjuvant/adjuvant Phase 3 KEYNOTE-522 trial investigating KEYTRUDA, Merck s anti-PD-1 therapy, in combination with chemotherapy as pre-operative (neoadjuvant) treatment and then continuing as a single agent (adjuvant) treatment after surgery. KEYNOTE-522 met its dual primary endpoint of event-free survival (EFS) for the treatment of patients with high-risk early-stage triple-negative breast cancer (TNBC). Based on an interim analysis conducted by the independent Data Monitoring Committee (DMC), neoadjuvant KEYTRUDA plus chemotherapy followed by adjuvant KEYTRUDA as monotherapy showed a statistically significant and clinically meaningful improvement in EFS compared with neoadjuvant chemotherapy alone.

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