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Does low testosterone make COVID-19 worse for men?

A new study suggests that, among men, low testosterone levels in the blood are linked to more severe COVID-19. The study contradicts widespread assumptions that higher testosterone may explain why men, on average, develop more severe COVID-19 than women do. “The groups of men who were getting sicker were known to have lower testosterone across the board.” Throughout the pandemic, doctors have seen evidence that men with COVID-19 fare worse, on average, than women with the infection. One theory is that hormonal differences between men and women may make men more susceptible to severe disease. And since men have much more testosterone than women, some scientists have speculated that high levels of testosterone may be to blame.

For men, low testosterone means high risk of severe COVID-19

 E-Mail IMAGE: A new study from Washington University School of Medicine in St. Louis suggests that, among men, low testosterone levels in the blood are linked to more severe COVID-19. The study. view more  Credit: SARA MOSER Throughout the pandemic, doctors have seen evidence that men with COVID-19 fare worse, on average, than women with the infection. One theory is that hormonal differences between men and women may make men more susceptible to severe disease. And since men have much more testosterone than women, some scientists have speculated that high levels of testosterone may be to blame. But a new study from Washington University School of Medicine in St. Louis suggests that, among men, the opposite may be true: that low testosterone levels in the blood are linked to more severe disease. The study could not prove that low testosterone is a cause of severe COVID-19; low levels could simply serve as a marker of some other causal factors. Still, the researchers ur

Triple-negative breast cancer more deadly for African American women

 E-Mail Multiple studies have shown that African American women with breast cancer have lower survival rates than white women with the disease. But the association between race or ethnicity and treatment outcomes in triple-negative breast cancer an aggressive type of tumor that does not respond to hormonal or other targeted therapies has not been well defined. Now, new research from Washington University School of Medicine in St. Louis shows that non-Hispanic African American women with triple-negative breast cancer also do not fare as well as non-Hispanic white women with this type of breast cancer. The study demonstrates the need for additional research to address disparities in cancer care and understand whether tumor biology or nonbiological reasons such as systemic racism or a combination of such factors may prevent African American women from receiving the same quality of care as white women.

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