National Vaccine Institute (NVI), led by Dr. Nakorn Premsri, Director, in close collaboration with the World Health Organization (WHO), led by Dr. Jos Vandelaer, WHO Representative to Thailand, organised an online seminar on “How to handle when the new variant arrives” on December 15, 2021. The panellists emphasised the importance of complete vaccination doses along with personal preventive measures in order to control the outbreak and efficiently reduce the risk of infection or severe illness from COVID-19.