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Control of genes could explain why females suffer worse virus infection – study

A university study could explain why females may suffer worse outcomes of virus infection such as Covid-19. Researchers from the University of Dundee’s School of Life Sciences found the control of genes on X chromosomes in females can cause much wider effects on cells than previously realised. The X chromosome – of which females have two and men have only one – contains more than 1,000 genes that are vital for cell development. However, a double dose of such gene products can be lethal, meaning one of the two chromosomes in female cells shuts down in a process known as X chromosome inactivation (XCI).

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