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Clarity establishes a US Center of Excellence for Targeted Copper Theranostics

Clarity establishes a US Center of Excellence for Targeted Copper Theranostics
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Clarity establishes a US Center of Excellence for Targeted Copper Theranostics

SYDNEY, June 28, 2023 /PRNewswire/ Clarity Pharmaceuticals (ASX: CU6) ("Clarity"), a clinical-stage radiopharmaceutical company with a mission to develop next-generation products that improve treatment outcomes for children and adults with cancer, is pleased to announce the establishment of a Center of Excellence at the Idaho Accelerator Center (IAC), a research facility operated by Idaho State University (ISU), for Targeted Copper Theranostics (TCTs). The IAC is a unique research facility operated by ISU located in southeast Idaho, US. It is the result of the Nuclear Science Application Project, providing opportunities for scientists and engineers from the University, the private sector and the national laboratories to utilise specialised nuclear facilities. Clarity is establishing the Center of Excellence at the IAC to advance research and development (R&D) of TCTs close to a source of copper-67 (Cu-67 or 67Cu) production. This investment will enable Clarity to effici

Clarity s theranostic prostate cancer trial advances to cohort 2

Clarity s theranostic prostate cancer trial advances to cohort 2

Highlights Cohort 1 of the SECuRE trial has been completed in 6 participants with metastatic castrate-resistant prostate cancer (mCRPC) who received therapy with 67Cu SAR-bisPSMA at the lowest dose level of 4GBq. No dose limiting toxicities (DLTs) have been reported in cohort 1. The Safety Review Committee (SRC) has recommended that the trial continues to cohort 2. Recruitment has opened at clinical sites in the United States (US) at the cohort 2 dose level of 8GBq and patients are currently in screening for all available slots. Additional therapy cycles of 67Cu SAR-bisPSMA have been requested by clinicians under the US Food and Drug Administration (FDA) Expanded Access Program (EAP). Early data from the EAP indicates positive effects of the lowest dose of 67Cu SAR-bisPSMA on lesions, demonstrated by SPECT-CT images, with reduction in Prostate Specific Antigen (PSA) levels. SYDNEY, May 24, 2023 /PRNewswire/ Clarity Pharmaceuticals(ASX: CU6) ("Clarity", "the Company&quo

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