For the first time, researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), and Genentech<u>, a member of the Roche Group,</u> found a way to enhance and extend LN expansion, and study how this phenomenon affects both the immune system and efficacy of vaccinations against tumors. While the oversized LNs maintained a normal tissue organization, they displayed altered mechanical features and hosted higher numbers of various immune cell types that commonly are involved in immune responses against pathogens and cancers. Importantly, “jump-starting” lymph node expansion prior to administering a traditional vaccine against a melanoma-specific model antigen led to more effective and sustained anti-tumor responses in mice.
How old is too old to run? — Harvard Gazette harvard.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from harvard.edu Daily Mail and Mail on Sunday newspapers.
The 128th Boston Marathon will feature a number of Terriers traversing the 26.2 miles to Copley Square. Here are the stories of six running for charity.