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Study reveals how high-sugar diets can worsen inflammatory bowel disease

According to a new study from the University of Pittsburgh, excess sugar inhibits cells that regenerate the colon lining in a mouse model of inflammatory bowe

United statesSemir beyazPitt gnotobiotic animal core laboratoryCold spring harbor laboratoryPitt school of medicinePitt medical scientist training programUniversity of pittsburghMolecular gastroenterologyTimothy handAnsen burrMedical scientist training programGnotobiotic animal core

Identifying Cancer Genes Multiple Personalities

A new method using the gene-editing tool CRISPR-Cas9 has been developed to model liver cancer tumor subtypes caused by mutations in the same genes. By targeting a single section of the mouse gene, Ctnnb1, researchers were able to produce two distinct tumor subtypes, enhancing protein activity to promote tumor growth, which could allow for the development of new therapeutic interventions in the future.

Semir beyazCold spring harbor laboratory assistant professorCold spring harbor laboratoryCold spring harborSamuel diamondNeuroscience newsletter

Identifying Cancer Genes Multiple Personalities – Eurasia Review

Identifying Cancer Genes Multiple Personalities – Eurasia Review
eurasiareview.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurasiareview.com Daily Mail and Mail on Sunday newspapers.

Semir beyazCold spring harbor laboratory assistant professor

Identifying cancer genes multiple personalit

Genetic mutations can result in certain diseases like liver and colon cancer. But these tumors can be difficult to study even the same genes can lead to different tumors in different people. CSHL researchers have devised a way to produce separate tumor subtypes in mice by targeting the same cancer-causing gene.

Semir beyazCold spring harbor laboratory assistant professor

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

Semir beyazEmily hendersonCold spring harbor laboratoryAssistant professorCold spring harborGene editingLiver cancer

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