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Researchers discover more accurate technique to study gene responsible for innate immunity
An infant s odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.
The IRAK4 gene instructs the production of a protein that plays a key role in the early recognition and response to invading pathogens.
Inherited mutations in this gene can cause an immune system disorder that leaves the body susceptible to recurrent infections of pus-forming pyogenic bacteria. Cases of IRAK4 deficiency are quite rare and only about 10 familial instances were identified so far in Japan.
HiroshimaJapanSatoshi-okadaEmily-hendersonHiroshima-universitySchool-of-biomedicalHealth-sciencesHiroshima-university-ledStudy-authorGraduate-schoolஹிரோஷிமாஜப்பான்