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Anti-Aging Nutraceutical Improves Muscle Remodeling and Glucose Metabolism in Older Women
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April 27, 2021
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Obesity and aging decrease levels of a metabolic factor found in all living cells and vital in keeping us healthy: nicotinamide adenine dinucleotide (NAD+). The bioavailability of nicotinamide mononucleotide (NMN) is the rate-limiting factor in the production of NAD+.
In a small-scale clinical trial (NCT03151239) and the first clinical trial on NMN, scientists at the Center for Human Nutrition at the Washington University School of Medicine found NMN supplementation enhances the ability of insulin to increase glucose uptake in skeletal muscles and improves expression of genes involved in muscle structure and remodeling in postmenopausal prediabetic women who are overweight or obese.
Anti-aging compound that improves metabolic health in mice improves muscle glucose metabolism in people | The Source wustl.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from wustl.edu Daily Mail and Mail on Sunday newspapers.
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In the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.
A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.
A small clinical trial of postmenopausal women with prediabetes shows that the compound NMN (nicotinamide mononucleotide) improved the ability of insulin to increase glucose uptake in skeletal muscle, which often is abnormal in people with obesity, prediabetes or Type 2 diabetes. NMN also improved expression of genes that are involved in muscle structure and remodeling. However, the treatment did not lower blood glucose or blood pressur
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