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In about 5% of patients with seropositive RA, C-reactive protein levels were normal despite disease flares during a 5-year period. The findings represent an "underappreciated, persistent phenotype."
The results highlight the need for close monitoring and optimized multidisciplinary care for long-term adverse events after COVID-19 in patients with rheumatic disease.
Although it’s possible the higher proportion of Omicron cases in vaccinated patients accounted for lower rates of long COVID, differences in variants likely couldn’t account for all the findings.