The importance of light scattering in particle analysis An important technique for measuring molecular weight, light scattering is a widely used tool for analysing biopolymers, polymers and proteins. Click to read more.
Glaukos Corporation (NYSE: GKOS), an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders and retinal diseases, announced
May 24 2021
The new HK Series Differential Refractometer from Testa Analytical Solutions eK sets a benchmark for precise determination of specific refractive index increment (dn/dc) - an important parameter for polymer and protein molecular weight determination using light scattering techniques.
The specific refractive index increment (dn/dc) is one of the most underestimated parameters in material science. The assumption that using the approximate values for many polymers and proteins in published literature will not have a huge impact on molecular weight values determined by light scattering experiments, with or without GPC/SEC separation is incorrect. Because dn/dc is a squared term in the Debye Constant of the Zimm equation, any error in determining dn/dc will result in introducing considerable errors into molecular weight determination. In addition to this, precise determination of dn/dc within a GPC/SEC application, is extremely useful in order to calculat