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email article Despite an arsenal of highly effective injectable vaccines, drugmakers are looking into products that will be easier to store, transport, and administer in the global crisis particularly, intranasal vaccines. Could these vaccines also hold an advantage when it comes to blocking transmission? While more data has suggested the vaccines authorized in the U.S. cut transmission, some experts have argued that intranasal vaccines may do an even better job of this. MedPage Today surveyed the global landscape of intranasal vaccines in development, the majority of which are in early stages. Rationale for COVID-19 Mucosal Vaccines The mucosal immune system represents the body s first line of defense against outside pathogens at surfaces like the nose, lungs, mouth, eyes, and GI tract. Because the nasopharynx is the primary entry point for SARS-CoV-2, targeting the nasal cavity could be one of the best lines of defense for vaccines, according to Michael Russell, PhD,

New yorkUnited statesRichard kennedyVeronica hackethalMichael russellCansino biologicsCodagenix serum institute of indiaWorld health organizationUniversity of hong kongCoalition for epidemic preparedness innovationsSerum research instituteCuba centerXiamen universityUniversity of oxford astrazeneca covishieldUniversity at buffaloPage today