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IMAGE: Mixscape separates a mixture of cells into perturbed (yellow) and non-perturbed ( escaping, grey) cells. view more
Credit: New York University/New York Genome Center
A team of researchers from New York University and the New York Genome Center has developed a new computational tool to help understand the function and regulation of human genes. The results, published today in the journal
Nature Genetics, demonstrate how to interpret experiments that combine the use of CRISPR to perturb genes along with multimodal single-cell sequencing technologies.
The article describes how the new approach, called mixscape, helped to identify a new molecular mechanism for the regulation of immune checkpoint proteins that govern the immune system s ability to identify and destroy cancer cells.
New Algorithm Identifies 'Escaping' Cells in Single-cell CRISPR Screens, Uncovers New Regulators of Immune Cell Behavior miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
New York University: New Algorithm Identifies 'Escaping' Cells in Single-cell CRISPR Screens, Uncovers New Regulators of Immune Cell Behavior – India Education,Education News India,Education News indiaeducationdiary.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from indiaeducationdiary.in Daily Mail and Mail on Sunday newspapers.
Synopsis
The company, formerly known as Lodha Developers, has been trying to sell shares in an initial public offering since 2009. Macrotech made the latest announcement in an exchange filing on Tuesday.
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A successful share sale will help the company, founded by a lawmaker from India’s ruling Bharatiya Janata Party, partially pay 80.8 billion rupees of liabilities due this year.
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By Rahul Satija and Dhwani Pandya
Macrotech Developers Ltd., India’s biggest homebuilder, plans to raise 25 billion rupees ($344 million) in an initial share sale to help reduce its massive debt burden.
The company, formerly known as Lodha Developers, has been trying to sell shares in an initial public offering since 2009. Macrotech made the latest announcement in an exchange filing on Tuesday.