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Kanazawa University Research: Metallic complexes made from cyclic molecules

Kanazawa University research: Color coding molecular mirror images

Kanazawa University research: Color coding molecular mirror images
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Kanazawa University research: Regulators for extracellular vesicle production

Kanazawa University research: Regulators for extracellular vesicle production
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Kanazawa University research: Solvent effects of siloxanes on donor-acceptor interactions

Kanazawa University research: Solvent effects of siloxanes on donor-acceptor interactions KANAZAWA, Japan, May 11, 2021 /PRNewswire/ Researchers at Kanazawa University report in Chemical Communications how solvents influence the strength of donor-acceptor interactions. They found that silicone solvents, providing low compatibility, intensify donor-acceptor interactions between aromatic molecules compared to hydrocarbon solvents. Aromatic donor-acceptor (D-A) interactions are a type of non-covalent bond between a donor (electron-rich) and an acceptor (electron-deficient) aromatic molecules. Aromatic molecules feature one or more rings with delocalized electrons. The aromatic D-A interactions are widely used for building supramolecular structures, which are assembly of molecules formed by non-covalent bonds like building blocks. The supramolecular structures have smart properties such as external stimuli-responsiveness and self-repairing. The stability and smart properties of

Kanazawa University research: Unraveling DNA packaging

Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters how high-speed atomic force microscopy can be used for studying DNA wrapping processes.  The technique enables visualizing the dynamics of DNA–protein interactions, which in certain cases resembles the motion of inchworms. The genetic material of most organisms is carried by DNA, a complex organic molecule.  DNA is very long for humans, the molecule is estimated to be about 2 m in length.  In cells, DNA occurs in a densely packed form, with strands of the molecule coiled up in a complicated but efficient space-filling way.  A key role in DNA s compactification is played by histones, structural-support proteins around which a part of a DNA molecule can wrap.  The DNA–histone wrapping process is reversible the two molecules can unwrap and rewrap but little is known about the mechanisms at play.  Now, by applying high-speed atomic-force microscopy (HS-AFM), Richard Wong and colleagu

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