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Atezolizumab Plus Neoadjuvant HP/Chemo Does Not Significantly Improve pCR in HER2+ Breast Cancer

The addition of atezolizumab to neoadjuvant trastuzumab plus pertuzumab (HP) and chemotherapy led to a numerical, but not statistically significant, increase in pathologic complete response vs HP/chemotherapy alone in patients with HER2-positive operable breast cancer.

San antonioUnited statesMenarini ricercheAptneo michelangeloLuca gianniBiomedical insights incDenali therapeutics incArtemida pharma ltdAntonio breast cancerInternational breast cancer research committeeFondazione michelangeloRevolution medicinesEuropean patent applicationAtezolizumab plus hp and chemotherapyPertuzumab and trastuzumabHer2 positive breast cancer

Evolving NSCLC Landscape: Comparing Recent Updates in Neoadjuvant and Perioperative Immunotherapy

An expert comparison of recent data on neoadjuvant and perioperative immunotherapy in resectable early-stage NSCLC, including CheckMate 77T, CheckMate-816, and KEYNOTE-671.

Women healthDigital healthPopulation healthComplete responseAdjuvant therapyPathologic complete responseCheckmate 816Checkmate 77tKeynote 671Neoadjuvant phaseNeoadjuvant immune checkpoint inhibitor

Study: Diet, exercise improve outcomes of chemotherapy for women with breast cancer

Study: Diet, exercise improve outcomes of chemotherapy for women with breast cancer
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Tara sanftMelinda irwinYale cancer centerYale school of public healthSmilow cancer hospital survivorshipClinical oncologyYale schoolPublic healthRandomized trialPathologic complete responseWomen with breast cancerNutrition early after diagnosis study

Trilaciclib Increases Pool of Memory T Cells in the Tumor Microenvironment Responsible for Long Term Immune Surveillance and Efficacy

Trilaciclib Increases Pool of Memory T Cells in the Tumor Microenvironment Responsible for Long Term Immune Surveillance and Efficacy
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United statesRaj malikResearch triangle parkExchange commissionTherapeutics incAmerican joint committee on cancerInvestor relations corporate communicationsAmerican society of clinical oncologyWall streetAction trial results demonstrateImmunomodulatory effectsTumor microenvironmentEnhances expressionGenes associatedMemoryt cellsIncreases multiple surrogate immune markers

Trilaciclib Increases Pool of Memory T Cells in the Tumor Microenvironment Responsible for Long Term Immune Surveillance and Efficacy

- Phase 2 Mechanism of Action Trial Results Demonstrate the Immunomodulatory Effects of Trilaciclib in the Tumor Microe.

United statesRaj malikTherapeutics incInvestor relations corporate communicationsExchange commissionResearch triangle parkAmerican joint committee on cancerAmerican society of clinical oncologyAction trial results demonstrateImmunomodulatory effectsTumor microenvironmentEnhances expressionGenes associatedMemoryt cellsIncreases multiple surrogate immune markersChief medical officer