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Researchers at Michigan Medicine found a subset of middle-aged men with cerebral palsy are up to 5.6 times more likely to suffer fractures than men without the disorder. We are not really sure why this happens, said Edward A. Hurvitz, M.D., professor and chair of the Michigan Medicine Department of Physical Therapy and Rehabilitation. It may be related to structural differences that occur during adolescent growth, or to greater bone mineral loss at earlier age for people with cerebral palsy compared to peers.
For a study published in
BONE, the team examined the timing and site of bone fractures for around 10 million people with and without cerebral palsy using public and private insurance claims from 2016. They found people with the disability have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population.
According to a pilot study published in ARRS American Journal of Roentgenology, the flexed elbow valgus external rotation (FEVER) view can improve MRI evaluation of the ulnar collateral ligament (UCL) in Major League Baseball pitchers. The increased joint space width confirms elbow valgus stress with FEVER view. Diagnostic confidence increased, and additional UCLs were identified as abnormal.
Regular strength and impact-type training may decrease or even prevent age-related bone deterioration in men, new research at the University of Jyväskylä, Finland, shows.
An international team of researchers, led by UC Davis Health, developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.
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IMAGE: The spinal cord of a mouse with ALS. The green cells are inhibitory interneurons. view more
Credit: Ilary Allodi, University of Copenhagen
ALS is a very severe neurodegenerative disease in which nerve cells in the spinal cord controlling muscles and movement slowly die. There is no effective treatment and the average life expectancy after being diagnosed with ALS is usually short. Because of this, new knowledge about the disease is urgently needed.
Now, researchers from the University of Copenhagen have gained new insights about ALS, by investigating the early development of the disease in a mouse model. We have found that networks of nerve cells in the spinal cord called inhibitory interneurons lose connection to motor neurons, the nerve cells that directly control muscle contraction. We do not yet know if these changes cause the disease. But the loss of the inhibitory signal could explain why the motor neurons end up dying in ALS , says first and co