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New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

Kateryna-kon-shutterstock
Memory-disorders-clinic-at-duke-university
Science-translational-medicine
Image-credit
Kateryna-kon
Memory-disorders-clinic
Biomarker
Flood
Na
Dna-damage
Arkinson-39s-disease
Amino-acid

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Researchers evaluated the use of a dual clustered regularly interspaced short palindromic repeats (CRISPR)-Cas3 system.

Stem-cell-reports
Image-credit
Crispr
Dystrophin
Enomic
Protein
Cas9
Fell
Duchenne-muscular-dystrophy
Exon
Nixons

Could automated, saliva-based PCR testing be the future of COVID-19 surveillance?

In a large-scale study funded by Kings College London, researchers successfully implemented an automated PCR-based testing program for SARS-CoV-2 using saliva samples from asymptomatic students and staff. The system achieved 85% sensitivity and 100% specificity, provided rapid results within eight hours, and offered a cost-effective and scalable approach to community surveillance of COVID-19.

London
City-of
United-kingdom
United-states
Pooja-toshniwal-pahariaaug
Pooja-toshniwal-paharia
United-kingdom-accreditation-service
Kings-college-london
Office-for-national-statistics
National-health-service-test
United-kingdom-department-of-health
United-states-centers-for-disease

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