Corona-Impfstoff von Novavax zeigt hohe Wirksamkeit | Wissen & Umwelt | DW dw.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from dw.com Daily Mail and Mail on Sunday newspapers.
Herd immunity is often presented as a simple mathematical calculation, but achieving it is far from easy. Understanding how widespread immunity works is, however, key to returning to normal.
Corona-Kreuzimpfung: Mehr als nur eine Notlösung? | Wissen & Umwelt | DW dw.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from dw.com Daily Mail and Mail on Sunday newspapers.
A new German study reports that a combination of the AstraZeneca and BioNTech vaccines triggers a remarkably stronger immune response than sticking with one kind of shot.
Concerns over AstraZeneca vaccine
How it works
It starts with the delivery of the gene for the Sars-CoV-2 spike protein. In vector-based vaccines, this is delivered via an adenoviral system, the scientists write.
The SARS-CoV-2 spike gene is then transcribed inside of the nucleus and subsequently exported as mRNA out of the nucleus. Arriving in the cytosol, the mRNA is again translated into the Spike protein. And exactly here lies the problem, the scientists write, the viral piece of DNA deriving from an RNA virus is not optimized to be transcribed inside of the nucleus.
In the nucleus, splicing of the spike protein can occur at splice sites.