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Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

Giovanni-cancemi
Nature-communications
Image-credit
Bacteria
Gonorrhea
Ntibiotic
Antibiotic-resistance
Antimicrobial-resistance
Binding-affinity
Blindness
Na
Ectopic-pregnancy

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

Richarde-kast
Study-center
Drugs
Adenocarcinoma
Ntibiotic
Azithromycin
Chemotherapy
Gemcitabine
Ncology
Paclitaxel
Research

Fungicide resistance: A global threat to human, animal, and plant health

Fungi can cause disease in both humans, animals, and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production.

Norway
Denmark
Norwegian
Ida-skaar
Andrea-ficke
World-health-organization
Norwegian-veterinary-institute
Norwegian-institute-of-bioeconomy-research
Norwegian-veterinary
One-health
Agriculture
Ntibiotic

Hormonal steroids could make gonorrhea untreatable

You know that package warning that oral birth control won't prevent STIs? Well in the case of gonorrhea, the sexually transmitted bacterium that causes the disease can use those hormones to help it resist antibiotic attacks.

Emily-cannistraci
Julius-caesar-roman
Richard-brennan
Nature-communications
Us-department-of-veterans-affairs
National-institutes-of-health
Centers-for-disease
Duke-university
Us-department-of-energy
Grace-hooks
Julius-caesar
Disease-control

Cirrhosis patients face mixed infection outcomes amid pandemic healthcare shifts

The COVID-19 pandemic's influence on healthcare systems led to mixed outcomes for patients with cirrhosis, showing stable infection rates but a rise in multi-drug resistant organism (MDRO) infections.

Gorodenkoff-shutterstock
Scientific-reports
Cirrhosis
Coronavirus-disease-covid-19
Pandemic
Ntibiotic
Antibiotic-resistance
Hronic
Coronavirus
Healthcare
Immune-system

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