However, the postmarketing study found two genetic polymorphisms that increase the risk of severe peripheral neuropathy. The study was published as a preprint and has not yet been peer reviewed.
Plinabulin plus pegfilgrastim had more efficacy than pegfilgrastim alone in ameliorating chemotherapy-induced neutropenia. The study was published as a preprint and has not yet been peer reviewed.
The addition of oxaliplatin does not extend progression-free survival in elderly patients with metastatic colorectal cancer and in fact, can lead to more severe adverse events.
Black women with metastatic triple-negative breast cancer have outcomes comparable to those of the overall patient population, shows a prespecified analysis of ASCENT.