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IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

Almost all postmenopausal patients aged 50-69 years with stage I hormone receptor (HR)-positive breast cancer and low scores on a common genetic test who opted out of adjuvant radiotherapy were disease free five years after surgery, according to results from the IDEA clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

San-antonio
Texas
United-states
American
Lawrencew-davis
Reshma-jagsi
Emory-university-school-of-medicine
Doris-duke-foundation
Winship-cancer-institute-of-emory-university
University-of-michigan-rogel-cancer-center
American-cancer-society
Susang-komen-breast-cancer-foundation

Sympathetic nervous system and immune interplay

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

Milieu-in-metabolic-health
Advanced-science
Sympathetic-immune-milieu
Metabolic-health
Image-credit
Nervous-system
Adipose
Flood
Fell
Cell-proliferation
Diabetes

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

United-states
Kateryna-kon
World-health-organization
Prostate-cancer
Its-transgenerational
Image-credit
Androgen-deprivation-therapy
Cancer
Obesity
Prostate
Prostate-cancer
Adipose

Women in low- and middle-income countries more likely to have obesity risk

Women in low- and middle-income countries, especially in the Sub-Saharan Africa region, may be 10 times more likely to have obesity or heart health issues than their male counterparts, according to a large meta-analysis published in The Journal of Clinical Endocrinology & Metabolism.

Madrid
Spain
London
City-of
United-kingdom
Javier-zamora
Wiebke-arlt
Lily-ramsey
Eka-melson
Shakila-thangaratinam
Borja-fernandez-felix
Universitario-ram

Socioeconomic status correlated with thyroid cancer diagnosis and death probability

The incidence of thyroid cancer in São Paulo State, part of Brazil's relatively developed Southeast region, varies considerably according to socioeconomic status (education, poverty, wealth, income, segregation, mobility, and access to resources and services) and access to screening, but is highest in higher-income areas and the state capital.

Brazil
Colombia
Barretos
Sãpaulo
Ecuador
Megan-craig
Adeylson-guimar
Paulo-cancer-foundation
World-health-organization
International-agency-for-research-on-cancer
National-cancer-institute
Paulo-state

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