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Tight Link Between Ambulatory BP and Mortality Affirmed in Revamped Analysis

The study follows a prior one retracted due to data problems, with the information now “rescued for reliable analyses.”

Comunidad autonoma de catalunaGiuseppe manciaBryan williamsNatalie staplinTerrassa university hospitalMd university of milanoUniversity of barcelonaPhd university of oxfordMd university college london hospitalsUniversity of oxfordUniversity college london hospitalsNew england journalAlejandro de la sierraSpanish ambulatory blood pressure registryInternal medicine

Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients

Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients
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United kingdomDaichi sankyoNatalie staplinNovo nordiskSpanish national institute of statisticsResearch council population health unitUniversity college londonBoehringer ingelheimSpanish national health systemSpanish society of hypertensionCare research biomedical centres oxfordUniversity of oxfordClinical trial service unitUniversity college london hospitalsNational institute for healthCare research biomedical centres at oxford

Evidence in favour of ambulatory blood pressure grows but gaps in knowledge remain

Evidence in favour of ambulatory blood pressure grows but gaps in knowledge remain
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Natalie staplinSpanish ambulatory blood pressure registryNew england journal

Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

In patients hospitalised for COVID-19 with clinical hypoxia who required either no oxygen or simple oxygen only, higher dose corticosteroids significantly increased the risk of death compared with usual care, which included low-dose corticosteroids. The RECOVERY trial continues to assess the effects of higher dose corticosteroids in patients hospitalised with COVID-19 who require non-invasive ventilation, invasive mechanical ventilation, or extracorporeal membrane oxygenation.

United kingdomNorthern irelandRaphl hamersDamodar paudelPeterw horbyMarian knightEdmund juszczakRichard haynesMark campbellRoshan kumar jhaEvelyne kestelynMarion mafhamDavid demetsThomas jakiMayah buchSauln faust

EMPA-Kidney Seals SGLT2 Inhibitors as Foundational for CKD

Empagliflozin s efficacy in a range of patients with chronic kidney disease in EMPA-Kidney filled evidence gaps and confirmed SGLT2 inhibitors as a key treatment regardless of diabetes status.

United statesUnited kingdomNatalie staplinPatrickb markJanani rangaswamiNaveed sattarAmerican heart associationBoehringer ingelheimUniversity of glasgowRenal studies group at oxford universityAmerican society of nephrologyGeorge washington university school of medicineNovo nordiskHealth sciencesNew england journalKidney week