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Growing neurons gain an edge by making connections A little competition is never a bad thing, especially when it comes to fledging neurons growing in the brain, finds a new Stanford University study. In a first of its kind study, researchers led by Stanford biologist Liqun Luo used genetic experiments and computer models to shed light on two important steps of brain development in young mice: the growth of branching extensions on the bodies of neurons, called dendrites, and the connections that dendrites make with other neurons. Like biological antennas, dendrites receive incoming signals from other neurons via connections called synapses. Luo’s team found that the dendrites of growing neurons compete with one another to form connections with their partners, and the presence of successful connections increases the odds of dendrite growth.

Liqun luoYukari takeoAndrew shusterLinnie jiangSurya ganguliNeurosciences program phNational institutes of healthHoward hughes medical instituteSwindells professor in stanford school of humanitiesBill swindells professorMosaic analysisDouble markerNeurosciences program phdAssociate professorNational institutesHoward hughes medical