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GPCR structure: Research reveals molecular origins of function for a key drug target

GPCR structure: Research reveals molecular origins of function for a key drug target
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

United kingdomGeorgej pedersenBrian kobilkaM madan babuMichel bouvierFranziska heydenreichPhilipps university of marburgStanford universityStanford university school of medicineJude research collaborativeUniversity of montrealDepartment of biochemistryLaboratory of molecular biologyJude department of structural biologyCancer of the university montrealCambridge university

St Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

United statesUnited kingdomM madan babuFranziska heydenreichMichel bouvierMaria marti solanoGeorgej pedersenManbir sandhuBrian kobilkaCambridge universityJude research collaborativeStanford university school of medicineAmerican heart associationCancer of the university montrealRoyal society universityNational institutes of health

GPCR structure: Research reveals molecular or

<p>Scientists at St. Jude Children’s Research Hospital reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands. </p>

United statesUnited kingdomM madan babuMaria marti solanoFranziska heydenreichBrian kobilkaChelsea bryantMichel bouvierManbir sandhuGeorgej pedersenLaboratory of molecular biologyEuropean union horizonDepartment of biochemistryStanford university school of medicineCancer of the university montrealJude department of structural biology

GPCR structure: Research reveals molecular origins of function for a key drug target

GPCR structure: Research reveals molecular origins of function for a key drug target
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

United kingdomGeorgej pedersenM madan babuBrian kobilkaFranziska heydenreichFranziskam heydenreichZhaowen luoMichel bouvierStanford university school of medicineJude research collaborativePhilipps university of marburgCambridge universityUniversity of montrealJude children research hospitalDepartment of biochemistryJude department of structural biology

Mutation accessibility fuels influenza evolution

Mutation accessibility fuels influenza evolution
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Alexander gunnarssonM madan babuJude department of hostJude department of structural biologyWorld health organization collaborating centre forJude departmentStructural biologyData driven discoveryRichard webbyHost microbe interactionsWorld health organization collaborating centre