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Study reports on safety of COVID-19 mRNA vaccines in pregnancy

Study reports on safety of COVID-19 mRNA vaccines in pregnancy Researchers used different surveillance systems in the United States to track adverse outcomes after coronavirus disease 2019 (COVID-19) vaccination in pregnant people and found no major safety flags. In the United States, mRNA vaccines were the first to receive emergency use authorization to combat COVID-19. However, these vaccines were not approved for use in pregnant women as the clinical trial did not include pregnant women, and there is very little data on the safety of the vaccines among pregnant women. However, pregnant women are more at risk of severe disease compared to the non-pregnant population. There may also be a greater risk of adverse outcomes like preterm birth. Hence, guidelines have been issued that pregnant women should also be given the vaccine. However, these women should be monitored after vaccination to determine safety.

How effective is the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine? A real-world study in Sweden

Investigating a population in southern Sweden, a new study has found that a single dose of the vaccine is only about 42% effective in preventing coronavirus disease 2019 (COVID-19). But seven days after the second dose, the vaccine can prevent COVID-19 in 86% of the population.

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Interfering RNA nanoparticles could be a potential COVID-19 therapy Study shows lipid nanoparticle-based siRNA is potent in suppressing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – in cells as well as in mice models. COVID-19 cases continue to increase all over the world. Several vaccines have now been approved and are being administered. However, with new variants of the virus emerging, there have been questions around how effective the vaccines will be. The genome in coronaviruses is encoded by ribonucleic acid (RNA), making them vulnerable to RNA interference, especially when they are delivered to the lungs. However, there are few therapies that target viral RNA.

Screening drug candidates for COVID-19 treatment using computational methods

Screening drug candidates for COVID-19 treatment using computational methods
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