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QF researchers report largest genetic association study in Middle East
08 May 2021 - 8:38
Prof Omar Albagha
The Peninsula
Doha: A group of researchers at Qatar Foundation have reported the first and largest genetic association study in the Middle East, that has been published online in Nature Communications a leading a peer-reviewed, open access, scientific journal published by Nature Research.
The study titled “Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits” highlights a vital piece of information wherein now there is a better understanding of the genetic risk factors that are specific to the Arab population, including those that are shared with other ethnicities.
QatarDohaAd-daw-ahQatariQatarisKarsten-suhreOmar-albaghaNature-communicationsCollege-of-healthNature-researchQatar-genome-research-consortiumQatar-foundation-qf-hamad-bin-khalifa-university 07 Apr 2021 - 20:19
The Peninsula
Doha: A study of proteins circulating in the bloodstream has identified several proteins that may play a causal role in obesity, making them potential targets for drugs and therapies.
Researchers at Weill Cornell Medicine – Qatar examined more than 1,000 proteins in samples taken from individuals in Qatar as part of the Qatar Metabolomics Study on Diabetes, alongside data from European studies. In total, more than 4,600 individuals were involved in the three previous studies. The work was conducted in collaboration with the German Research Center for Environmental Health.
Using genetics to isolate the relevant proteins, they found that six proteins had a causal relationship with body mass index, even when other lifestyle factors were taken into consideration. Three of those proteins were found to contribute towards obesity, and at the same time, reflect the biological mechanisms resulting from increased body mass index.
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